[Evaluation of SCC antigen in patients with advanced cervix cancer treated with radiation]. / Ocena antygenu SCC u chorych na zaawansowanego raka szyjki macicy, leczonych promieniami.

The TA-4 antigen was isolated and described in 1977 by Kato and Torigoe. The antigen called SCC-squamous cell carcinoma is subfraction TA-4 isolated of liver metastases from cervix uteri. The cut-off limits for SCC-antigen is counted as 1.5-2.5 ng/ml. The level of SCC-antigen was determined in the serum of 41 women with advanced cervix uteri cancer-IIIB and IV FIGO stage. The value of SCC-antigen was evaluated twice: before and after the treatment. The increasing of SCC-level was observed in the serum of 80% women. The conclusion are: There was the lowering of SCC-antigen value in patients after the irradiation. In cases of patients who still had high SCC-antigen level after the treatment and it exceeded 8 ng/ml., progression of cancer also was found. The progression of cancer after the treatment was found in women with pretreatment level of SCC-antigen higher than 30 ng/ml.