Long-term maintenance of drug-metabolizing enzyme activities in rat hepatocytes after cryopreservation.

Fautrel, A; Joly, B; Guyomard, C; Guillouzo, A

Fautrel, A; Joly, B; Guyomard, C; Guillouzo, A.

Affiliation

Fautrel A; INSERM U 456, Université de Rennes I, Rennes, France.

Toxicol Appl Pharmacol ; 147(1): 110-4, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9356313

Subject(s)

Cryopreservation; Cytochrome P-450 CYP1A1/metabolism; Cytochrome P-450 CYP2B1/metabolism; Liver/enzymology; Acetaminophen/chemistry; Acetaminophen/metabolism; Acetylation; Animals; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP2B1/analysis; Dimethyl Sulfoxide/chemistry; Epithelial Cells/cytology; Glucuronates/chemistry; Liver/cytology; Liver/physiology; Phenacetin/analysis; Phenacetin/metabolism; Rats; Rats, Sprague-Dawley

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Collection: 01-internacional Database: MEDLINE Main subject: Cryopreservation / Cytochrome P-450 CYP1A1 / Cytochrome P-450 CYP2B1 / Liver Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 1997 Document type: Article Affiliation country: France

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