Adenomyoepithelioma of the skin: a case report with immunohistochemical and ultrastructural observations.
Histopathology
; 31(4): 374-7, 1997 Oct.
Article
in En
| MEDLINE
| ID: mdl-9363454
ABSTRACT
AIMS:
The histological, immunohistochemical and electron microscopic features of a primary adenomyoepithelioma of skin, a rare sweat gland tumour, are reported. METHODS ANDRESULTS:
The tumour occurred on the back of a 92-year-old woman. It was composed of well-formed tubules lined by epithelial cells surrounded by clear or spindled myoepithelial cells. Immunohistochemically, the epithelial cells exhibited strong cytokeratin (CAM5.2) and weak carcinoembryonic antigen positivity. The myoepithelial cells showed diffuse positivity for smooth muscle actin and focal positivity for S100 protein. Ultrastructurally, the myoepithelial cells contained myofilaments with focal densities and hemidesmosomes. They were limited by well-formed basal lamina. The tumour was associated with a small eccrine spiradenoma.CONCLUSION:
We predict that the tumour will behave in a benign fashion. There is no evidence of recurrence or metastasis 28 months later.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sweat Gland Neoplasms
/
Adenomyoma
/
Myoepithelioma
Type of study:
Prognostic_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
En
Journal:
Histopathology
Year:
1997
Document type:
Article
Affiliation country:
United kingdom