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Development of a testicular haemangioma after interferon therapy for hepatic haemangiomas: a case report.
Yanai, S; Tsutsumi, H; Hotsubo, T; Takahashi, A; Miyao, N; Satoh, M; Chiba, S.
Affiliation
  • Yanai S; Department of Paediatrics, Sapporo Medical University School of Medicine, Japan.
Eur J Pediatr ; 156(10): 784-6, 1997 Oct.
Article in En | MEDLINE | ID: mdl-9365068
UNLABELLED: We report a 2-month-old Japanese boy presenting with large multiple haemangiomas invading his liver. He was treated with daily subcutaneous injection of interferon alfa (IFN-alpha)-2a with progressive reduction of the hepatic haemangioma. He developed a scrotal mass 2 months after discontinuation of IFN, and this mass eventually required surgical management. Resected tumour was a juvenile haemangioma. The escape of this haemangioma from IFN therapy may be correlated to the quite low level of injected IFN in testis. CONCLUSION: IFN therapy may not be curative for testicular haemangioma although it is effective in shrinking haemangiomas of the liver and skin.
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Collection: 01-internacional Database: MEDLINE Main subject: Testicular Neoplasms / Neoplasms, Second Primary / Interferon-alpha / Hemangioma / Liver Neoplasms Type of study: Diagnostic_studies Limits: Humans / Infant / Male Language: En Journal: Eur J Pediatr Year: 1997 Document type: Article Affiliation country: Japan Country of publication: Germany
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Collection: 01-internacional Database: MEDLINE Main subject: Testicular Neoplasms / Neoplasms, Second Primary / Interferon-alpha / Hemangioma / Liver Neoplasms Type of study: Diagnostic_studies Limits: Humans / Infant / Male Language: En Journal: Eur J Pediatr Year: 1997 Document type: Article Affiliation country: Japan Country of publication: Germany