Quaternary pilocarpine derivatives as potential acetylcholine antagonists. 2. Alterations in the lactone and imidazole moieties.

Ben-Bassat, A A; Lavie, D

Ben-Bassat, A A; Lavie, D.

J Med Chem ; 19(7): 928-33, 1976 Jul.

Article in En | MEDLINE | ID: mdl-940111

Subject(s)

Acetylcholine/antagonists & inhibitors; Pilocarpine/analogs & derivatives; Animals; Antidotes; Guinea Pigs; Imidazoles/chemical synthesis; In Vitro Techniques; Lactones/chemical synthesis; Male; Mice; Muscle Contraction/drug effects; Muscle, Smooth/drug effects; Organophosphate Poisoning; Pilocarpine/chemical synthesis; Pilocarpine/pharmacology; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Pilocarpine / Acetylcholine Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1976 Document type: Article

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