Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation.

Hayek, T; Fuhrman, B; Vaya, J; Rosenblat, M; Belinky, P; Coleman, R; Elis, A; Aviram, M

Hayek, T; Fuhrman, B; Vaya, J; Rosenblat, M; Belinky, P; Coleman, R; Elis, A; Aviram, M.

Affiliation

Hayek T; Lipid Research Laboratory, Rambam Medical Center, Haifa, Israel.

Arterioscler Thromb Vasc Biol ; 17(11): 2744-52, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9409251

Subject(s)

Antioxidants/therapeutic use; Apolipoproteins E/deficiency; Arteriosclerosis/prevention & control; Catechin/therapeutic use; Free Radical Scavengers/therapeutic use; Lipoproteins, LDL/metabolism; Quercetin/therapeutic use; Wine; Animals; Aorta/pathology; Aortic Diseases/pathology; Aortic Diseases/prevention & control; Apolipoproteins E/genetics; Arteriosclerosis/genetics; Arteriosclerosis/pathology; Cholesterol, LDL/metabolism; Disease Progression; Drug Evaluation, Preclinical; Foam Cells/pathology; Lipoproteins, LDL/biosynthesis; Lipoproteins, LDL/chemistry; Macrophages/metabolism; Mice; Mice, Knockout; Oxidation-Reduction; Particle Size; Wine/analysis

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Arteriosclerosis / Quercetin / Wine / Catechin / Free Radical Scavengers / Lipoproteins, LDL / Antioxidants Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 1997 Document type: Article Affiliation country: Israel

Search on Google

Add to My VHL

XML

PubMed Links