Liver LDL receptor mRNA expression is decreased in human ApoB/CETP double transgenic mice and is regulated by diet as well as the cytokine oncostatin M.

Liu, J; Zhang, Y L; Spence, M J; Vestal, R E; Wallace, P M; Grass, D S

Liu, J; Zhang, Y L; Spence, M J; Vestal, R E; Wallace, P M; Grass, D S.

Affiliation

Liu J; Department of Veterans Affairs Medical Center, Boise, Idaho, USA. Liu@icon.Palo-Alto.med.VA.gov

Arterioscler Thromb Vasc Biol ; 17(11): 2948-54, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9409281

Subject(s)

Apolipoproteins B/physiology; Carrier Proteins/physiology; Cholesterol, Dietary/pharmacology; Gene Expression Regulation/drug effects; Glycoproteins; Liver/metabolism; Peptides/pharmacology; RNA, Messenger/biosynthesis; Receptors, LDL/biosynthesis; Animal Feed; Animals; Apolipoproteins B/genetics; Carrier Proteins/genetics; Cholesterol/blood; Cholesterol Ester Transfer Proteins; Cholesterol, Dietary/toxicity; Feedback; Gene Expression Regulation/genetics; Genotype; Humans; Hypercholesterolemia/etiology; Hypercholesterolemia/genetics; Hypercholesterolemia/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oncostatin M; Polymerase Chain Reaction; Receptors, LDL/genetics; Recombinant Proteins/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins B / Peptides / RNA, Messenger / Receptors, LDL / Cholesterol, Dietary / Glycoproteins / Carrier Proteins / Gene Expression Regulation / Liver Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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