Immunization with a syngeneic tumor infected with recombinant vaccinia virus expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) induces tumor regression and long-lasting systemic immunity.

McLaughlin, J P; Abrams, S; Kantor, J; Dobrzanski, M J; Greenbaum, J; Schlom, J; Greiner, J W

McLaughlin, J P; Abrams, S; Kantor, J; Dobrzanski, M J; Greenbaum, J; Schlom, J; Greiner, J W.

Affiliation

McLaughlin JP; Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

J Immunother ; 20(6): 449-59, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9409450

Subject(s)

Adenocarcinoma/immunology; Cancer Vaccines; Colonic Neoplasms/immunology; Granulocyte-Macrophage Colony-Stimulating Factor/genetics; Immunization; Vaccinia virus/genetics; Adenocarcinoma/prevention & control; Animals; Cell Line; Colonic Neoplasms/prevention & control; Female; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism; Haplorhini; Kidney; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Recombinant Proteins; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Vaccinia virus / Adenocarcinoma / Granulocyte-Macrophage Colony-Stimulating Factor / Immunization / Colonic Neoplasms / Cancer Vaccines Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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