Altered expression of tropomodulin in cardiomyocytes disrupts the sarcomeric structure of myofibrils.

Sussman, M A; Baqué, S; Uhm, C S; Daniels, M P; Price, R L; Simpson, D; Terracio, L; Kedes, L

Sussman, M A; Baqué, S; Uhm, C S; Daniels, M P; Price, R L; Simpson, D; Terracio, L; Kedes, L.

Affiliation

Sussman MA; Department of Biochemistry and Molecular Biology and the Institute for Genetic Medicine, University of Southern California School of Medicine, Los Angeles, USA. sussman@heart.chmcc.org

Circ Res ; 82(1): 94-105, 1998.

Article in En | MEDLINE | ID: mdl-9440708

Subject(s)

Carrier Proteins/genetics; Microfilament Proteins; Myocardium/metabolism; Myofibrils/metabolism; Actins/metabolism; Adenoviridae/genetics; Adenoviridae/physiology; Animals; Carrier Proteins/physiology; Cells, Cultured; DNA, Recombinant; Gene Expression/genetics; Gene Expression/physiology; Genetic Vectors/genetics; Humans; Mice; Myocardium/cytology; Myofibrils/ultrastructure; Myofibrils/virology; Proteins/metabolism; RNA, Messenger/metabolism; RNA, Viral/metabolism; Rats; Sarcomeres/chemistry; Sarcomeres/ultrastructure; Sarcomeres/virology; Transfection/genetics; Transfection/physiology; Tropomodulin

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Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Microfilament Proteins / Myocardium / Myofibrils Limits: Animals / Humans Language: En Journal: Circ Res Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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