Improved high-performance liquid chromatographic assay for the determination of procainamide and its N-acetylated metabolite in plasma: application to a single-dose pharmacokinetic study.

Lessard, E; Fortin, A; Coquet, A; Bélanger, P M; Hamelin, B A; Turgeon, J

Lessard, E; Fortin, A; Coquet, A; Bélanger, P M; Hamelin, B A; Turgeon, J.

Affiliation

Lessard E; Faculty of Pharmacy, Laval University and Quebec Heart Institute, Laval Hospital, Sainte-Foy, Canada.

J Chromatogr Sci ; 36(1): 49-54, 1998 Jan.

Article in En | MEDLINE | ID: mdl-9443381

Subject(s)

Acecainide/blood; Anti-Arrhythmia Agents/blood; Procainamide/blood; Acetylation; Anti-Arrhythmia Agents/pharmacokinetics; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Procainamide/pharmacokinetics; Regression Analysis; Spectrophotometry, Ultraviolet

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Collection: 01-internacional Database: MEDLINE Main subject: Procainamide / Acecainide / Anti-Arrhythmia Agents Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Chromatogr Sci Year: 1998 Document type: Article Affiliation country: Canada

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