Characterization of the mevalonate kinase 5'-untranslated region provides evidence for coordinate regulation of cholesterol biosynthesis.

Bishop, R W; Chambliss, K L; Hoffmann, G F; Tanaka, R D; Gibson, K M

Bishop, R W; Chambliss, K L; Hoffmann, G F; Tanaka, R D; Gibson, K M.

Affiliation

Bishop RW; Geron Corporation, Menlo Park, California 94025, USA.

Biochem Biophys Res Commun ; 242(3): 518-24, 1998 Jan 26.

Article in En | MEDLINE | ID: mdl-9464248

Subject(s)

Cholesterol/biosynthesis; Gene Expression Regulation/genetics; Phosphotransferases (Alcohol Group Acceptor)/genetics; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; COS Cells; Chloramphenicol O-Acetyltransferase/genetics; Cloning, Molecular; Genes, Reporter; Humans; Lipoproteins/deficiency; Lipoproteins/metabolism; Lovastatin/pharmacology; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor)/chemistry; Promoter Regions, Genetic/genetics; RNA, Messenger/metabolism; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Transcription, Genetic/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Cholesterol / Phosphotransferases (Alcohol Group Acceptor) Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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