Higher risk of preeclampsia in the polycystic ovary syndrome. A case control study.
Eur J Obstet Gynecol Reprod Biol
; 76(1): 91-5, 1998 Jan.
Article
in En
| MEDLINE
| ID: mdl-9481555
ABSTRACT
OBJECTIVE:
To determine whether the risk of pregnancy-induced hypertensive disorders (PIHD) is higher in patients with the polycystic ovary syndrome (PCOS) than in non-PCOS controls, matched for age and parity. STUDYDESIGN:
Retrospective analysis of eighty-one patients with PCOS, consecutively becoming pregnant during a seven-year period. Each PCOS-patient was matched for age and parity with one control patient. Chi-squared, Mann-Whitney or Fisher's exact-tests were used for statistical analysis.RESULTS:
Overall incidence of PIHD was similar in both study groups. However, incidence of preeclampsia was significantly higher in patients with PCOS than in controls (P = 0.02). This higher incidence can not be explained by body mass index, endocrine profile before pregnancy, induction of ovulation or treatment regimens.CONCLUSIONS:
PCOS-patients are at a significantly higher risk for preeclampsia than non-PCOS controls.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polycystic Ovary Syndrome
/
Pre-Eclampsia
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Eur J Obstet Gynecol Reprod Biol
Year:
1998
Document type:
Article
Affiliation country:
Netherlands
Country of publication:
IE
/
IRELAND
/
IRLANDA