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Suppression subtractive hybridization (SSH) identifies prolactin stimulation of p38 MAP kinase gene expression in Nb2 T lymphoma cells: molecular cloning of rat p38 MAP kinase.
Nemeth, E; Bole-Feysot, C; Tashima, L S.
Affiliation
  • Nemeth E; Pacific Biomedical Research Center, University of Hawaii, Honolulu 96822, USA.
J Mol Endocrinol ; 20(1): 151-6, 1998 Feb.
Article in En | MEDLINE | ID: mdl-9513091
Suppression Subtractive Hybridization (SSH) has been used to compare rat Nb2 cells treated with prolactin for 1 hour with untreated cells. This new method for identifying differentially expressed genes showed that the mRNAs for at least three genes were elevated by such treatment, including a p38 mitogen activated protein (MAP) kinase. The p38 MAP kinase was cloned and the full length cDNA sequence was determined.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Prolactin / Gene Expression Regulation, Enzymologic / Lymphoma, T-Cell / Calcium-Calmodulin-Dependent Protein Kinases / Mitogen-Activated Protein Kinases Limits: Animals Language: En Journal: J Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1998 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Collection: 01-internacional Database: MEDLINE Main subject: Prolactin / Gene Expression Regulation, Enzymologic / Lymphoma, T-Cell / Calcium-Calmodulin-Dependent Protein Kinases / Mitogen-Activated Protein Kinases Limits: Animals Language: En Journal: J Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1998 Document type: Article Affiliation country: United States Country of publication: United kingdom