Inter- and intraquinolone predictors of antimicrobial effect in an in vitro dynamic model: new insight into a widely used concept.

Firsov, A A; Shevchenko, A A; Vostrov, S N; Zinner, S H

Firsov, A A; Shevchenko, A A; Vostrov, S N; Zinner, S H.

Affiliation

Firsov AA; Department of Pharmacokinetics, Centre of Science & Technology LekBioTech, Moscow, Russia. biotec@glas.apc.org

Antimicrob Agents Chemother ; 42(3): 659-65, 1998 Mar.

Article in En | MEDLINE | ID: mdl-9517948

Subject(s)

Anti-Infective Agents/pharmacokinetics; Ciprofloxacin/pharmacokinetics; Escherichia coli/metabolism; Fluoroquinolones; Klebsiella pneumoniae/metabolism; Naphthyridines/pharmacokinetics; Pseudomonas aeruginosa/metabolism; Area Under Curve; Colony Count, Microbial; Escherichia coli/drug effects; Escherichia coli/growth & development; Klebsiella pneumoniae/drug effects; Klebsiella pneumoniae/growth & development; Microbial Sensitivity Tests; Pseudomonas aeruginosa/drug effects; Pseudomonas aeruginosa/growth & development; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Ciprofloxacin / Fluoroquinolones / Escherichia coli / Klebsiella pneumoniae / Anti-Infective Agents / Naphthyridines Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Antimicrob Agents Chemother Year: 1998 Document type: Article Affiliation country: RUSSIA

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