Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse.

Dahlén, E; Dawe, K; Ohlsson, L; Hedlund, G

Dahlén, E; Dawe, K; Ohlsson, L; Hedlund, G.

Affiliation

Dahlén E; Pharmacia & Upjohn, Lund Research Center, Sweden.

J Immunol ; 160(7): 3585-93, 1998 Apr 01.

Article in En | MEDLINE | ID: mdl-9531322

Subject(s)

Dendritic Cells/metabolism; Islets of Langerhans/immunology; Macrophages/metabolism; Tumor Necrosis Factor-alpha/biosynthesis; Animals; Biomarkers/analysis; Cell Movement/immunology; Dendritic Cells/chemistry; Dendritic Cells/pathology; Female; Islets of Langerhans/metabolism; Islets of Langerhans/pathology; Kinetics; Macrophages/chemistry; Macrophages/pathology; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Staining and Labeling; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; T-Lymphocytes/pathology; Tumor Necrosis Factor-alpha/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Islets of Langerhans / Tumor Necrosis Factor-alpha / Macrophages Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 1998 Document type: Article Affiliation country: Sweden

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