Novel lactone compounds from Mortierella verticillata that induce the human low density lipoprotein receptor gene: fermentation, isolation, structural elucidation and biological activities.

Dekker, K A; Aiello, R J; Hirai, H; Inagaki, T; Sakakibara, T; Suzuki, Y; Thompson, J F; Yamauchi, Y; Kojima, N

Dekker, K A; Aiello, R J; Hirai, H; Inagaki, T; Sakakibara, T; Suzuki, Y; Thompson, J F; Yamauchi, Y; Kojima, N.

Affiliation

Dekker KA; Central Research Division, Pfizer Pharmaceuticals Inc., Aichi, Japan.

J Antibiot (Tokyo) ; 51(1): 14-20, 1998 Jan.

Article in En | MEDLINE | ID: mdl-9531982

Subject(s)

Lactones; Lactones/chemistry; Lactones/isolation & purification; Mucorales/chemistry; Receptors, LDL/genetics; Cell Culture Techniques; Fermentation; Gene Expression Regulation; Humans; Lactones/pharmacology; Macrolides/chemistry; Macrolides/isolation & purification; Macrolides/pharmacology; Mucorales/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Lactones / Mucorales Limits: Humans Language: En Journal: J Antibiot (Tokyo) Year: 1998 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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