Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma.

Gorlick, R; Metzger, R; Danenberg, K D; Salonga, D; Miles, J S; Longo, G S; Fu, J; Banerjee, D; Klimstra, D; Jhanwar, S; Danenberg, P V; Kemeny, N; Bertino, J R

Gorlick, R; Metzger, R; Danenberg, K D; Salonga, D; Miles, J S; Longo, G S; Fu, J; Banerjee, D; Klimstra, D; Jhanwar, S; Danenberg, P V; Kemeny, N; Bertino, J R.

Affiliation

Gorlick R; Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

J Clin Oncol ; 16(4): 1465-9, 1998 Apr.

Article in En | MEDLINE | ID: mdl-9552053

Subject(s)

Adenocarcinoma/enzymology; Colorectal Neoplasms/pathology; Gene Expression Regulation, Neoplastic; Liver Neoplasms/enzymology; Lung Neoplasms/enzymology; Thymidylate Synthase/genetics; Adenocarcinoma/drug therapy; Adenocarcinoma/secondary; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Blotting, Western; Female; Fluorouracil/administration & dosage; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms/drug therapy; Liver Neoplasms/secondary; Lung Neoplasms/drug therapy; Lung Neoplasms/secondary; Male; Middle Aged; Polymerase Chain Reaction; RNA, Messenger/genetics; Thymidylate Synthase/analysis

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Thymidylate Synthase / Colorectal Neoplasms / Adenocarcinoma / Gene Expression Regulation, Neoplastic / Liver Neoplasms / Lung Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Oncol Year: 1998 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links