Biotransformation of irbesartan in man.

Chando, T J; Everett, D W; Kahle, A D; Starrett, A M; Vachharajani, N; Shyu, W C; Kripalani, K J; Barbhaiya, R H

Chando, T J; Everett, D W; Kahle, A D; Starrett, A M; Vachharajani, N; Shyu, W C; Kripalani, K J; Barbhaiya, R H.

Affiliation

Chando TJ; Department of Metabolism and Pharmacokinetics, The Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA.

Drug Metab Dispos ; 26(5): 408-17, 1998 May.

Article in En | MEDLINE | ID: mdl-9571222

Subject(s)

Antihypertensive Agents/pharmacokinetics; Biphenyl Compounds/pharmacokinetics; Tetrazoles/pharmacokinetics; Antihypertensive Agents/administration & dosage; Antihypertensive Agents/blood; Antihypertensive Agents/urine; Biotransformation; Biphenyl Compounds/administration & dosage; Biphenyl Compounds/blood; Biphenyl Compounds/urine; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Irbesartan; Male; Reference Values; Tetrazoles/administration & dosage; Tetrazoles/blood; Tetrazoles/urine

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Collection: 01-internacional Database: MEDLINE Main subject: Tetrazoles / Biphenyl Compounds / Antihypertensive Agents Type of study: Clinical_trials Limits: Humans / Male Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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