Unconventional rapid Erk1,2 activation is indispensable for proliferation of the growth factor-independent myeloid leukemic cell line KG1.

Barge, R M; Dorrestijn, J; Falkenburg, J H; Willemze, R; Maassen, J A

Barge, R M; Dorrestijn, J; Falkenburg, J H; Willemze, R; Maassen, J A.

Affiliation

Barge RM; Department of Hematology, University Medical Centre, Leiden, The Netherlands.

Leukemia ; 12(5): 699-704, 1998 May.

Article in En | MEDLINE | ID: mdl-9593267

Subject(s)

Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Interleukin-3/pharmacology; Leukemia, Myeloid/enzymology; Leukemia, Myeloid/pathology; Mitogen-Activated Protein Kinases; Cell Division/physiology; Enzyme Activation; Enzyme Inhibitors/pharmacology; Flavonoids/pharmacology; Humans; Interleukin-3/physiology; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase C/deficiency; Protein Kinase C/metabolism; Proteins/metabolism; Shc Signaling Adaptor Proteins; Signal Transduction/physiology; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; ras Proteins/biosynthesis; ras Proteins/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid / Interleukin-3 / Calcium-Calmodulin-Dependent Protein Kinases / Mitogen-Activated Protein Kinases / Adaptor Proteins, Vesicular Transport / Adaptor Proteins, Signal Transducing Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 1998 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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