[Evaluation of antiviral activity of new medicinal forms of foscarnet in genital herpes in guinea pigs]. / Otsenka protivovirusnoi aktivnosti novykh lekarstvennykh form foskarneta pri genital'nom gerpese morskikh svinok.
Vopr Virusol
; 43(2): 82-6, 1998.
Article
in Ru
| MEDLINE
| ID: mdl-9606877
ABSTRACT
Antiviral activity of a Russian drug foscarnet (tablets and coated pills) was assessed in guinea pigs with experimental genital herpes. New dosage forms were well tolerated by the animals, causing no manifest symptoms of intoxication irrespective of the doses or protocols of the drug use, Foscarnet in any dosage form in the total daily dose of at least 120 mg/kg had a pronounced antiviral effect towards herpes simplex type II virus, comparable with that of the commercial reference drug virolex the intensity of clinical symptoms was alleviated and the disease duration shortened.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Herpes Genitalis
/
Foscarnet
Type of study:
Guideline
Limits:
Animals
Language:
Ru
Journal:
Vopr Virusol
Year:
1998
Document type:
Article
Publication country:
FEDERAÇÃO RUSSA
/
RU
/
RUSIA
/
RUSSIA