Evidence that histamine is the principal pharmacological component of venom from an Australian wolf spider (Lycosa godeffroyi).

Rash, L D; King, R G; Hodgson, W C

Rash, L D; King, R G; Hodgson, W C.

Affiliation

Rash LD; Department of Pharmacology, Monash University, Clayton, Victoria, Australia.

Toxicon ; 36(2): 367-75, 1998 Feb.

Article in En | MEDLINE | ID: mdl-9620584

Subject(s)

Histamine Antagonists/pharmacology; Histamine/pharmacology; Muscle Contraction/drug effects; Muscle, Smooth, Vascular/drug effects; Spider Venoms/pharmacology; Animals; Aorta/drug effects; Australia; Blood Pressure/drug effects; Bronchoconstriction/drug effects; Fluorometry; Guinea Pigs; Histamine/analysis; Ileum/drug effects; Male; Pyrilamine/pharmacology; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spider Venoms/antagonists & inhibitors; Spider Venoms/chemistry; Vas Deferens/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Spider Venoms / Histamine / Histamine Antagonists / Muscle Contraction / Muscle, Smooth, Vascular Limits: Animals Country/Region as subject: Oceania Language: En Journal: Toxicon Year: 1998 Document type: Article Affiliation country: Australia Country of publication: United kingdom

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