The prototypic Th2 autoimmunity induced by mercury is dependent on IFN-gamma and not Th1/Th2 imbalance.

Kono, D H; Balomenos, D; Pearson, D L; Park, M S; Hildebrandt, B; Hultman, P; Pollard, K M

Kono, D H; Balomenos, D; Pearson, D L; Park, M S; Hildebrandt, B; Hultman, P; Pollard, K M.

Affiliation

Kono DH; Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA. dkono@scripps.edu

J Immunol ; 161(1): 234-40, 1998 Jul 01.

Article in En | MEDLINE | ID: mdl-9647229

Subject(s)

Autoimmune Diseases/chemically induced; Interferon-gamma/physiology; Mercuric Chloride/immunology; Th1 Cells/immunology; Th2 Cells/immunology; Animals; Autoantibodies/biosynthesis; Autoimmune Diseases/genetics; Autoimmune Diseases/immunology; Disease Susceptibility; Dose-Response Relationship, Immunologic; Haptens/immunology; Interferon-gamma/genetics; Interleukin-4/biosynthesis; Interleukin-4/deficiency; Interleukin-4/genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrophenols/immunology; Phenylacetates; Th1 Cells/metabolism; Th2 Cells/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Interferon-gamma / Th2 Cells / Th1 Cells / Mercuric Chloride Limits: Animals Language: En Journal: J Immunol Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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