Neutrophils deficient in PU.1 do not terminally differentiate or become functionally competent.

Anderson, K L; Smith, K A; Pio, F; Torbett, B E; Maki, R A

Anderson, K L; Smith, K A; Pio, F; Torbett, B E; Maki, R A.

Affiliation

Anderson KL; The Burnham Institute and the Department of Immunology, The Scripps Research Institute, La Jolla, CA, USA.

Blood ; 92(5): 1576-85, 1998 Sep 01.

Article in En | MEDLINE | ID: mdl-9716585

Subject(s)

Cell Differentiation; DNA-Binding Proteins/metabolism; Neutrophils/cytology; Neutrophils/physiology; Trans-Activators/deficiency; Trans-Activators/metabolism; Animals; Cells, Cultured; Chemotaxis, Leukocyte; Cytoplasmic Granules/genetics; DNA-Binding Proteins/physiology; Granulocyte Colony-Stimulating Factor/pharmacology; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; Interferon Regulatory Factors; Interleukin-8/pharmacology; Macrophage Colony-Stimulating Factor/pharmacology; Mice; N-Formylmethionine Leucyl-Phenylalanine/pharmacology; NADPH Oxidases/genetics; Neutrophil Activation; Phagocytosis; Phenotype; RNA, Messenger/analysis; Superoxides/metabolism; Tetradecanoylphorbol Acetate/pharmacology; Trans-Activators/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Trans-Activators / DNA-Binding Proteins / Neutrophils Limits: Animals Language: En Journal: Blood Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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