Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis.

Li, G; Segu, V B; Rabaglia, M E; Luo, R H; Kowluru, A; Metz, S A

Li, G; Segu, V B; Rabaglia, M E; Luo, R H; Kowluru, A; Metz, S A.

Affiliation

Li G; Medical Service, Middleton Veterans Administration Hospital, Madison, Wisconsin 53705, USA. nmiligd@med2.nusstf.nus.sg

Endocrinology ; 139(9): 3752-62, 1998 Sep.

Article in En | MEDLINE | ID: mdl-9724027

Subject(s)

Apoptosis/physiology; Bacterial Proteins; Guanosine Triphosphate/deficiency; Insulin/metabolism; Islets of Langerhans/physiology; Animals; Apoptosis/drug effects; Bacterial Toxins/pharmacology; GTP-Binding Proteins/physiology; Insulin Secretion; Islets of Langerhans/metabolism; Lovastatin/pharmacology; Mitosis/physiology; Mycophenolic Acid/pharmacology; Rats; Rats, Sprague-Dawley; Time Factors

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Islets of Langerhans / Apoptosis / Guanosine Triphosphate / Insulin Limits: Animals Language: En Journal: Endocrinology Year: 1998 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links