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The deafness-associated mitochondrial DNA mutation at position 7445, which affects tRNASer(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression.
Guan, M X; Enriquez, J A; Fischel-Ghodsian, N; Puranam, R S; Lin, C P; Maw, M A; Attardi, G.
Affiliation
  • Guan MX; Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.
Mol Cell Biol ; 18(10): 5868-79, 1998 Oct.
Article in En | MEDLINE | ID: mdl-9742104
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA Precursors / RNA, Transfer, Ser / Gene Expression Regulation, Enzymologic / RNA Processing, Post-Transcriptional / Mutation / NADH Dehydrogenase Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: Oceania Language: En Journal: Mol Cell Biol Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA Precursors / RNA, Transfer, Ser / Gene Expression Regulation, Enzymologic / RNA Processing, Post-Transcriptional / Mutation / NADH Dehydrogenase Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: Oceania Language: En Journal: Mol Cell Biol Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States