Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation.

Kalinski, P; Schuitemaker, J H; Hilkens, C M; Kapsenberg, M L

Kalinski, P; Schuitemaker, J H; Hilkens, C M; Kapsenberg, M L.

Affiliation

Kalinski P; Academic Medical Center, Department of Cell Biology and Histology, University of Amsterdam, The Netherlands. p.kalinski@amc.uva.nl

J Immunol ; 161(6): 2804-9, 1998 Sep 15.

Article in En | MEDLINE | ID: mdl-9743339

Subject(s)

Antigens, CD1/analysis; Dendritic Cells/immunology; Dendritic Cells/metabolism; Dinoprostone/pharmacology; Immunoglobulins/analysis; Interleukin-12/deficiency; Membrane Glycoproteins/analysis; Adjuvants, Immunologic/pharmacology; Antigens, CD; Cell Differentiation/drug effects; Cell Differentiation/immunology; Dendritic Cells/cytology; Dendritic Cells/drug effects; Drug Synergism; Humans; Immunophenotyping; Interleukin-1/pharmacology; Interleukin-10/pharmacology; Interleukin-12/biosynthesis; Interleukin-12/metabolism; Th2 Cells/metabolism; Tumor Necrosis Factor-alpha/pharmacology; CD83 Antigen

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Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Immunoglobulins / Membrane Glycoproteins / Dinoprostone / Interleukin-12 / Antigens, CD1 Limits: Humans Language: En Journal: J Immunol Year: 1998 Document type: Article Affiliation country: Netherlands Country of publication: United States

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