Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines.

Civoli, F; Daniel, L W

Civoli, F; Daniel, L W.

Affiliation

Civoli F; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1016, USA.

Cancer Chemother Pharmacol ; 42(4): 319-26, 1998.

Article in En | MEDLINE | ID: mdl-9744778

Subject(s)

Antineoplastic Agents/pharmacology; Phospholipid Ethers/pharmacology; Protein Kinase C/antagonists & inhibitors; Quaternary Ammonium Compounds/pharmacology; Cell Differentiation/drug effects; Cell Division/drug effects; Cell Survival/drug effects; Culture Media, Serum-Free; Drug Resistance; Enzyme Activation/drug effects; Furans/pharmacology; HL-60 Cells; Humans; Phosphorylcholine/analogs & derivatives; Phosphorylcholine/pharmacology; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / Phospholipid Ethers / Quaternary Ammonium Compounds / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Chemother Pharmacol Year: 1998 Document type: Article Affiliation country: United States Country of publication: Germany

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