Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.

Viard, I; Wehrli, P; Bullani, R; Schneider, P; Holler, N; Salomon, D; Hunziker, T; Saurat, J H; Tschopp, J; French, L E

Viard, I; Wehrli, P; Bullani, R; Schneider, P; Holler, N; Salomon, D; Hunziker, T; Saurat, J H; Tschopp, J; French, L E.

Affiliation

Viard I; Department of Dermatology, Geneva University Medical School, CH-1211 Geneva 4, Switzerland.

Science ; 282(5388): 490-3, 1998 Oct 16.

Article in En | MEDLINE | ID: mdl-9774279

Subject(s)

Apoptosis; Immunoglobulins, Intravenous/therapeutic use; Keratinocytes/pathology; Stevens-Johnson Syndrome/therapy; fas Receptor/physiology; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Blocking/immunology; Antibodies, Blocking/therapeutic use; Child; Dermis/pathology; Disease Progression; Epidermis/pathology; Fas Ligand Protein; Female; Humans; Jurkat Cells; Keratinocytes/metabolism; Male; Membrane Glycoproteins/metabolism; Middle Aged; Pilot Projects; Stevens-Johnson Syndrome/pathology; fas Receptor/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Keratinocytes / Stevens-Johnson Syndrome / Immunoglobulins, Intravenous / Apoptosis / Fas Receptor Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Science Year: 1998 Document type: Article Affiliation country: Switzerland Country of publication: United States

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