Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases.

Krumme, D; Wenzel, H; Tschesche, H

Krumme, D; Wenzel, H; Tschesche, H.

Affiliation

Krumme D; Universität Bielefeld, Fakultät für Chemie, Abteilung Biochemie I, Germany.

FEBS Lett ; 436(2): 209-12, 1998 Oct 02.

Article in En | MEDLINE | ID: mdl-9781680

Subject(s)

Hydroxamic Acids/pharmacology; Matrix Metalloproteinase Inhibitors; Oligopeptides/pharmacology; Protease Inhibitors/pharmacology; Humans; Hydroxamic Acids/chemical synthesis; Hydroxamic Acids/chemistry; Kinetics; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Oligopeptides/chemical synthesis; Oligopeptides/chemistry; Protease Inhibitors/chemistry; Structure-Activity Relationship; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Protease Inhibitors / Matrix Metalloproteinase Inhibitors / Hydroxamic Acids Limits: Humans Language: En Journal: FEBS Lett Year: 1998 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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