Rapid adenoviral transduction of freshly resected tumour explants with therapeutically useful genes provides a rationale for genetic immunotherapy for colorectal cancer.

Diaz, R M; Todryk, S; Chong, H; Hart, I R; Sikora, K; Dorudi, S; Vile, R G

Diaz, R M; Todryk, S; Chong, H; Hart, I R; Sikora, K; Dorudi, S; Vile, R G.

Affiliation

Diaz RM; Richard Dimbleby Department of Cancer Research/ICRF Laboratory, Rayne Institute, St Thomas' Hospital, London, UK.

Gene Ther ; 5(7): 869-79, 1998 Jul.

Article in En | MEDLINE | ID: mdl-9813657

Subject(s)

Adenoviridae; Colorectal Neoplasms/therapy; Cytokines/genetics; Genetic Vectors; Immunotherapy/methods; Transfection; Animals; Antimetabolites/therapeutic use; B7-1 Antigen/genetics; Colorectal Neoplasms/genetics; Colorectal Neoplasms/metabolism; Ganciclovir/therapeutic use; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor/genetics; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism; Interleukin-2/genetics; Interleukin-2/metabolism; Mice; Mice, Inbred Strains; Thymidine Kinase/genetics; Tumor Cells, Cultured

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Transfection / Colorectal Neoplasms / Adenoviridae / Cytokines / Genetic Vectors / Immunotherapy Type of study: Guideline / Prognostic_studies Limits: Animals Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 1998 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links