Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir.

Gambhir, S S; Barrio, J R; Wu, L; Iyer, M; Namavari, M; Satyamurthy, N; Bauer, E; Parrish, C; MacLaren, D C; Borghei, A R; Green, L A; Sharfstein, S; Berk, A J; Cherry, S R; Phelps, M E; Herschman, H R

Gambhir, S S; Barrio, J R; Wu, L; Iyer, M; Namavari, M; Satyamurthy, N; Bauer, E; Parrish, C; MacLaren, D C; Borghei, A R; Green, L A; Sharfstein, S; Berk, A J; Cherry, S R; Phelps, M E; Herschman, H R.

Affiliation

Gambhir SS; Crump Institute for Biological Imaging, Department of Molecular and Medical Pharmacology, UCLA-Jonsson Comprehensive Cancer Center, UCLA School of Medicine, Los Angeles, California 90095-1770, USA.

J Nucl Med ; 39(11): 2003-11, 1998 Nov.

Article in En | MEDLINE | ID: mdl-9829598

Subject(s)

Antiviral Agents; Ganciclovir; Genes, Reporter; Herpesvirus 1, Human/enzymology; Thymidine Kinase/genetics; Tomography, Emission-Computed; Adenoviridae; Animals; Autoradiography; Cells, Cultured; Feasibility Studies; Gene Expression; Genes, Viral; Herpesvirus 1, Human/genetics; Humans; Liver/diagnostic imaging; Mice; Rats; Tissue Distribution; Tomography, Emission-Computed/methods

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Thymidine Kinase / Tomography, Emission-Computed / Ganciclovir / Herpesvirus 1, Human / Genes, Reporter Limits: Animals / Humans Language: En Journal: J Nucl Med Year: 1998 Document type: Article Affiliation country: United States

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