Minimal tumor necrosis factor receptor binding protein: optimum biological activity of a truncated p55 soluble tumor necrosis factor receptor-IgG fusion protein.

Corcoran, A E; Scallon, B J; Trinh, H; Chernajovsky, Y; Ghrayeb, J; Feldmann, M

Corcoran, A E; Scallon, B J; Trinh, H; Chernajovsky, Y; Ghrayeb, J; Feldmann, M.

Affiliation

Corcoran AE; The Mathilda and Terence Kennedy Institute of Rheumatology, Sunley Division, Hammersmith, London, England.

Eur Cytokine Netw ; 9(3): 255-62, 1998 Sep.

Article in En | MEDLINE | ID: mdl-9831174

Subject(s)

Antigens, CD/physiology; Receptors, Tumor Necrosis Factor/physiology; Animals; Antigens, CD/chemistry; Antigens, CD/genetics; Cell Survival/drug effects; Dimerization; Gene Expression Regulation; Humans; Immunoglobulin Constant Regions; Immunoglobulin G/chemistry; Immunoglobulin G/metabolism; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Lipopolysaccharides/antagonists & inhibitors; Lipopolysaccharides/toxicity; Lymphotoxin-alpha/toxicity; Mice; Models, Molecular; Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor/chemistry; Receptors, Tumor Necrosis Factor/genetics; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Recombinant Fusion Proteins/therapeutic use; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Antigens, CD / Receptors, Tumor Necrosis Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur Cytokine Netw Journal subject: ALERGIA E IMUNOLOGIA Year: 1998 Document type: Article Affiliation country: United kingdom

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