Interaction of the fungal pathogen Candida albicans with integrin CD11b/CD18: recognition by the I domain is modulated by the lectin-like domain and the CD18 subunit.

Forsyth, C B; Plow, E F; Zhang, L

Forsyth, C B; Plow, E F; Zhang, L.

Affiliation

Forsyth CB; The Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Department of Molecular Cardiology, The Cleveland Clinic Foundation, OH 44195, USA.

J Immunol ; 161(11): 6198-205, 1998 Dec 01.

Article in En | MEDLINE | ID: mdl-9834106

Subject(s)

CD18 Antigens/metabolism; Candida albicans/immunology; Lectins/metabolism; Macrophage-1 Antigen/metabolism; Peptide Fragments/metabolism; CD18 Antigens/genetics; CD18 Antigens/physiology; Candida albicans/pathogenicity; Cell Adhesion/genetics; Cell Adhesion/immunology; Cell Line; Humans; Interleukin-2/pharmacology; Kidney; Lectins/immunology; Lectins/physiology; Lymphocyte Activation; Lymphocytes/immunology; Lymphocytes/microbiology; Macrophage-1 Antigen/genetics; Macrophage-1 Antigen/physiology; Models, Molecular; Peptide Fragments/immunology; Peptide Fragments/physiology; Peptide Mapping; Protein Binding/immunology; Protein Structure, Tertiary; Transfection/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Candida albicans / Macrophage-1 Antigen / CD18 Antigens / Lectins Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Immunol Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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