Cardioprotective actions of KC 12291. II. Delaying Na+ overload in ischemia improves cardiac function and energy status in reperfusion.

Hartmann, M; Decking, U K; Schrader, J

Hartmann, M; Decking, U K; Schrader, J.

Affiliation

Hartmann M; Institut für klinische Anästhesiologie, Heinrich-Heine-Universität Düsseldorf, Germany.

Naunyn Schmiedebergs Arch Pharmacol ; 358(5): 554-60, 1998 Nov.

Article in En | MEDLINE | ID: mdl-9840424

Subject(s)

Cardiovascular Agents/pharmacology; Heart/drug effects; Thiadiazoles/pharmacology; Adenosine Triphosphate/metabolism; Animals; Blood Pressure/drug effects; Cardiovascular Agents/therapeutic use; Energy Metabolism/drug effects; Guinea Pigs; Heart/physiopathology; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardial Ischemia/metabolism; Myocardial Ischemia/physiopathology; Myocardial Ischemia/prevention & control; Myocardial Reperfusion; Myocardium/metabolism; Phosphocreatine/drug effects; Phosphocreatine/metabolism; Sodium/metabolism; Thiadiazoles/therapeutic use; Ventricular Dysfunction, Left/prevention & control; Ventricular Function, Left/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Thiadiazoles / Cardiovascular Agents / Heart Limits: Animals Language: En Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 1998 Document type: Article Affiliation country: Germany Country of publication: Germany

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