Selection for carriers of recessive diseases: a common phenomenon?
Am J Med Genet
; 80(3): 266-8, 1998 Nov 16.
Article
in En
| MEDLINE
| ID: mdl-9843051
ABSTRACT
Several autosomal recessive disorders are present in high frequency in isolated populations because of either multiple allelic mutations or mutations in different genes. These observations are best explained by selection, which may be an important mechanism in the determination of the distribution of genetic disorders.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Selection, Genetic
/
Genes, Recessive
/
Heterozygote
Limits:
Humans
Language:
En
Journal:
Am J Med Genet
Year:
1998
Document type:
Article
Affiliation country:
Israel