Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells.

Seidel, A; Friedberg, T; Löllmann, B; Schwierzok, A; Funk, M; Frank, H; Holler, R; Oesch, F; Glatt, H

Seidel, A; Friedberg, T; Löllmann, B; Schwierzok, A; Funk, M; Frank, H; Holler, R; Oesch, F; Glatt, H.

Affiliation

Seidel A; Institute of Toxicology, University of Mainz, Germany. aseidel@goofy.zdv.uni-mainz.de

Carcinogenesis ; 19(11): 1975-81, 1998 Nov.

Article in En | MEDLINE | ID: mdl-9855012

Subject(s)

Carcinogens/metabolism; Epoxy Compounds/metabolism; Glutathione Transferase/metabolism; Isoenzymes/metabolism; Mutagens/metabolism; Polycyclic Aromatic Hydrocarbons/metabolism; Animals; Bay-Region, Polycyclic Aromatic Hydrocarbon; Cell Line; Cricetinae; Glutathione S-Transferase pi; Humans; Inactivation, Metabolic; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Polycyclic Aromatic Hydrocarbons / Carcinogens / Epoxy Compounds / Glutathione Transferase / Isoenzymes / Mutagens Limits: Animals / Humans Language: En Journal: Carcinogenesis Year: 1998 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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