Construction and characterization of a triple-recombinant vaccinia virus encoding B7-1, interleukin 12, and a model tumor antigen.

Carroll, M W; Overwijk, W W; Surman, D R; Tsung, K; Moss, B; Restifo, N P

Carroll, M W; Overwijk, W W; Surman, D R; Tsung, K; Moss, B; Restifo, N P.

Affiliation

Carroll MW; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892-1502, USA.

J Natl Cancer Inst ; 90(24): 1881-7, 1998 Dec 16.

Article in En | MEDLINE | ID: mdl-9862625

Subject(s)

Antigens, Neoplasm/genetics; B7-1 Antigen/genetics; Cancer Vaccines/genetics; Interleukin-12/genetics; Neoplasms, Experimental/therapy; Vaccinia virus/genetics; Animals; B7-1 Antigen/immunology; Blotting, Western; Cancer Vaccines/therapeutic use; Escherichia coli/enzymology; Escherichia coli/genetics; Feasibility Studies; Female; Flow Cytometry; Interleukin-12/immunology; Lac Operon; Lung Neoplasms/secondary; Lung Neoplasms/therapy; Mice; Mice, Inbred BALB C; Pentosyltransferases/genetics; Tumor Cells, Cultured; Vaccinia virus/immunology; beta-Galactosidase/genetics; beta-Galactosidase/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccinia virus / B7-1 Antigen / Interleukin-12 / Cancer Vaccines / Antigens, Neoplasm / Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Natl Cancer Inst Year: 1998 Document type: Article Affiliation country: United States

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