Toxicokinetics of inhaled 2-butoxyethanol and its major metabolite, 2-butoxyacetic acid, in F344 rats and B6C3F1 mice.

Dill, J A; Lee, K M; Bates, D J; Anderson, D J; Johnson, R E; Chou, B J; Burka, L T; Roycroft, J H

Dill, J A; Lee, K M; Bates, D J; Anderson, D J; Johnson, R E; Chou, B J; Burka, L T; Roycroft, J H.

Affiliation

Dill JA; Preclinical Drug Development-Northwest Operations, Battelle, Richland, Washington, USA.

Toxicol Appl Pharmacol ; 153(2): 227-42, 1998 Dec.

Article in En | MEDLINE | ID: mdl-9878593

Subject(s)

Ethylene Glycols/pharmacokinetics; Glycolates/pharmacokinetics; Solvents/pharmacokinetics; Administration, Inhalation; Age Factors; Animals; Dose-Response Relationship, Drug; Ethylene Glycols/blood; Ethylene Glycols/urine; Female; Male; Metabolic Clearance Rate; Mice; Rats; Rats, Inbred F344; Sex Characteristics; Species Specificity; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Ethylene Glycols / Glycolates Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 1998 Document type: Article Affiliation country: United States

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