Immunization with human immunodeficiency virus type 1 rgp120W61D in QS21/MPL adjuvant primes T cell proliferation and C-C chemokine production to multiple epitopes within variable and conserved domains of gp120W61D.

Jones, G J; von Hoegen, P; Weber, J; Rees, A D

Jones, G J; von Hoegen, P; Weber, J; Rees, A D.

Affiliation

Jones GJ; GU Medicine and Communicable Diseases, Imperial College School of Medicine at St. Mary's, London, W2 1PG, United Kingdom. gareth.jones@ic.ac.uk

J Infect Dis ; 179(3): 558-66, 1999 Mar.

Article in En | MEDLINE | ID: mdl-9952361

Subject(s)

AIDS Vaccines; Chemokines, CC/biosynthesis; HIV Envelope Protein gp120/immunology; HIV-1/immunology; Lymphocyte Activation; T-Lymphocytes/immunology; Vaccines, Synthetic; Amino Acid Sequence; Amino Acid Substitution; CD4-Positive T-Lymphocytes; Cell Line; Chemokines, CC/genetics; Conserved Sequence; Epitopes/chemistry; Epitopes/immunology; HIV Envelope Protein gp120/chemistry; HIV Envelope Protein gp120/genetics; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins/chemistry; Recombinant Proteins/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Vaccines, Synthetic / Lymphocyte Activation / T-Lymphocytes / HIV Envelope Protein gp120 / HIV-1 / AIDS Vaccines / Chemokines, CC Limits: Humans Language: En Journal: J Infect Dis Year: 1999 Document type: Article Affiliation country: United kingdom Country of publication: United States

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