Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus.

Kass, E; Schlom, J; Thompson, J; Guadagni, F; Graziano, P; Greiner, J W

Kass, E; Schlom, J; Thompson, J; Guadagni, F; Graziano, P; Greiner, J W.

Affiliation

Kass E; Laboratory of Tumor Immunology and Biology, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

Cancer Res ; 59(3): 676-83, 1999 Feb 01.

Article in En | MEDLINE | ID: mdl-9973217

Subject(s)

Cancer Vaccines/therapeutic use; Carcinoembryonic Antigen/immunology; Neoplasms, Experimental/prevention & control; Vaccinia virus/genetics; Vaccinia virus/immunology; Animals; Antibody Formation/immunology; Antibody Specificity; Cancer Vaccines/genetics; Cancer Vaccines/immunology; Carcinoembryonic Antigen/genetics; Female; Humans; Immunity, Cellular/immunology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental/immunology; Neoplasms, Experimental/metabolism; Polymerase Chain Reaction; Recombinant Proteins/genetics; Recombinant Proteins/immunology; Recombinant Proteins/metabolism; Vaccination; Vaccinia virus/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Vaccinia virus / Carcinoembryonic Antigen / Cancer Vaccines / Neoplasms, Experimental Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Res Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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