Familial granulomatous hepatitis: a hitherto unrecognized entity

ABSTRACT

Two West Indian parents and three of their seven offspring presented over a 12 yr period with identical systemic illnesses characterized by the development of granulomatous hepatitis. Granulomata were variably also found in muscle, lymph nodes, and pleura in some of these affected individuals. The usual causes of granulomatous hepatitis were absent, and this familial disease represents a hitherto undescribed entity. (AU)