Gallstones in sickle cell disease: observations from the Jamaican Cohort study

Walker, Tom M; Hambleton, Ian R; Serjeant, Graham R

Walker, Tom M; Hambleton, Ian R; Serjeant, Graham R.

J Pedriatr ; 136(1): 80-5, Jan. 2000.

Article in English | MedCarib | ID: med-749

Responsible library: JM3.1

Localization: JM3.1; RJ1.J6

ABSTRACT

ABSTRACT

The prevalence, incidence, risk factors, clinical associations, and morbidity of gallstones were studied in 311 patients with homozygous sickle cell disease and 167 patients with sickle cell-hemoglobin C disease in a cohort study from birth. Gallstones developed in 96 patients with homozygous sickle cell disease and 18 patients with sickle cell-hemoglobin C disease; specific symptoms necessitating cholecystectomy occurred in only 7 patients with homozygous sickle cell disease.(AU)

Subject(s)

Adult; Child; Humans; Male; Female; Adolescent; Anemia, Sickle Cell/epidemiology; Cholelithiasis/epidemiology; Hemoglobin SC Disease/epidemiology; Anemia, Sickle Cell/genetics; Anemia, Sickle Cell/mortality; Cholecystectomy; Cholelithiasis/complications; Cholelithiasis/surgery; Cohort Studies; Follow-Up Studies; Hemoglobin SC Disease/mortality; Homozygote; Incidence; Jamaica/epidemiology; Population Surveillance; Prevalence; Risk Factors; Survival Rate

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Collection: International databases Database: MedCarib Main subject: Cholelithiasis / Hemoglobin SC Disease / Anemia, Sickle Cell Type of study: Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Limits: Adolescent / Adult / Child / Female / Humans / Male Country/Region as subject: English Caribbean / Jamaica Language: English Journal: J Pedriatr Year: 2000 Document type: Article

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