Progress of Research on Risk Factors Associated With Primary Bile Reflux / 胃肠病学

ABSTRACT

Bile reflux (BR) can promote the development of chronic gastritis, gastric intestinal metaplasia, gastroesophageal reflux disease, gastric cancer and esophageal cancer. Secondary bile reflux (SBR) develops after pylorectomy or pylorus changed by gastrectomy or subtotal gastrectomy. Primary bile reflux (PBR) develops without surgery of stomach and is a very common phenomenon. This article reviewed the progress of research on risk factors associated with PBR.