Value of age shock index in predicting rebleeding and death in patients with liver cirrhosis complicated with acute portal vein thrombosis treated with TIPS / 中国医师杂志

ABSTRACT

Objective:To investigate the value of age shock index (Age-SI) in predicting rebleeding and death in patients with liver cirrhosis complicated with acute portal vein thrombosis treated by transjugular intrahepatic portosystemic shunt (TIPS).Methods:A total of 134 patients with liver cirrhosis complicated with acute portal vein thrombosis treated in West China Hospital of Sichuan University from April 2019 to April 2021 were selected, all patients were treated with TIPS, the differences of clinical data between rebleeding and no rebleeding, death and survival were observed and analyzed.Results:The age, child Pugh grade C ratio, Age-SI and neutrophil lymphocyte ratio (NLR) of patients with rebleeding were (57.28±9.92)years, 42.11%, (54.68±7.8) and (4.40±0.92), respectively, which were significantly higher than those of patients without rebleeding ( P<0.05). The age of dead patients, the course of liver cirrhosis, Age-SI and NLR were (59.90±9.81)years, (60.86±9.82)months, (55.47±7.64) and (4.76±0.99), respectively, which were significantly higher than those of surviving patients ( P<0.05). Logistic regression analysis showed that age, Age-SI and NLR were the influencing factors of rebleeding ( P<0.05), and Age, course of liver cirrhosis and Age-SI were the influencing factors of death ( P<0.05). The area under the receiver operating characteristic (ROC) curve for predicting rebleeding by Age-SI was 0.862( P<0.05); The area under the ROC curve for predicting death by Age-SI was 0.854 ( P<0.05). Conclusions:Age-SI has high application value in predicting rebleeding and death in patients with liver cirrhosis complicated with acute portal vein thrombosis treated with TIPS, which is worthy of further study.