Simultaneous content determination of eight Schisandra lignans in Hugan Tablets by UPLC / 中成药
Chinese Traditional Patent Medicine
; (12): 10-14, 2024.
Article
in Zh
| WPRIM
| ID: wpr-1028724
Responsible library:
WPRO
ABSTRACT
AIM To establish a UPLC method for the simultaneous content determination of schisandrol A,gomisin J,schisandrol B,angeloylgomisin H,angeloylgomisin Q,schisanhenol,deoxyschizandrin and schisandrin C in Waigan Fenghan Granules.METHODS The analysis was performed on a 40℃thermostatic WELCH Ultimate?-C18 column(100 mm×2.1 mm,1.8 μm),with the mobile phase comprising of acetonitrile-0.1%formic acid flowing at 0.3 mL/min in a gradient elution manner,and the detection wavelength was set at 267 nm.RESULTS Eight Schisandra lignans showed good linear relationships within their own ranges(R2≥0.998 3),whose average recoveries were 96.47%-104.96%with the RSDs of 0.62%-1.60%.CONCLUSION This simple,rapid and accurate method can be used for the quality control of Hugan Tablets.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Traditional Patent Medicine
Year:
2024
Document type:
Article