Progress in research on action mechanism of macrophages against herpes simplex virus type 1 infection / 中国生物制品学杂志

ABSTRACT

@#Herpes simplex virus type 1(HSV-1)is a DNA virus renowned for its ability to evade the immune response,establish latency,and reinfect.Despite extensive research into its biological characteristics,there are no specific therapeutics or preventative vaccines currently available for HSV-1.Infection with HSV-1 triggers innate and adaptive immune responses in the host,with macrophages playing a crucial role in antiviral immune responses through processes such as pathogen engulfment,processing,and presentation.This review aims to elucidate the latest research developments on the role of macrophages in combating HSV-1 infection,in hopes of providing insights for future vaccine design and drug development.