Influencing factors of diagnostic time in adult Moyamoya disease / 中华神经医学杂志

ABSTRACT

Objective To investigate the influencing factors of diagnostic time in adult moyamoya disease (MMD) and provide evidence for its early diagnosis. Methods The clinical data of 65 consecutive patients, admitted to our hopspital from August 2008 to December 2009, were retrospectively analyzed. Logistic regression nalysis was employed to confirm the relevant factors of diagnostic time. Results The 65 patients with early diagnosis and late diagnosis were 41 (63.1%) and 24 (36.9%), respectively. The percentage of patients firstly visiting a hospital with the third grade, patients with high education and high income, and patients having initial hemorrhage of the early diagnosis group was significantly higher than that in those of late diagnosis group (P<0.05). Through a logistic regression analysis, the grade of initial hospital, the level of education, initial symptom and economic level were significantly associated with the early diagnosis, and the patients having initial hemorrhage and firstly visiting a hospital with higher grade were diagnosed earlier (OR=3.401, 95%CI 1.301-8.892, P=0.013;OR=26.351, 95%CI 4.953-140.193, P=0.000). Conclusion Patients with MMD having initial hemorrhage and firstly visiting a hospital with the third grade can be early diagnosed.