Recent advance in histone deacetylation in epilepsy pathogenesis and treatment / 中华神经医学杂志
Chinese Journal of Neuromedicine
; (12): 422-428, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1035832
Responsible library:
WPRO
ABSTRACT
Epilepsy is a complex neurological disease and its pathogenesis has not yet been clear. More and more evidence shows that epilepsy is closely related to epigenetic mechanisms such as histone deacetylation. Histone deacetylase inhibitors, a kind of epilepsy targeting drug potentially, are involved in the protection of neurogenesis and the regulation of a variety of neural signal cascade reactions. This article reviews the research progress of histone deacetylation in the pathogenesis of epilepsy and application prospect of histone deacetylase inhibitors in treating epilepsy.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Neuromedicine
Year:
2023
Document type:
Article