Laparoscopic and Percutaneous Ultrasound Guided Radiofrequency Ablation for Hepatocellular Carcinoma: a Preliminary Study / 대한간학회지
The Korean Journal of Hepatology
; : 209-217, 2002.
Article
in Ko
| WPRIM
| ID: wpr-109816
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS: Radiofrequency ablation (RFA) is emerging as a new therapeutic method in the management of hepatocellular carcinoma (HCC). We report the results of 64 patients with a follow-up interval of 3 to 19 months. METHOD: Sixty-four patients with 82 nodules underwent ultrasound guided RFA. The mean tumor diameter was 2.5+/-1.0 cm. Laparoscopic ultrasound guided RFA was performed in 38 cases, and percutaneous ultrasound guided RFA in 26 cases. The therapeutic efficacy was evaluated by means of three-phase dynamic abdominal computed tomography (CT) performed within at least one week after ablating. The recurrence was evaluated after treatment by means of abdominal CT and alpha fetoprotein every 3 months. We calculated cumulative recurrence rates, survival rates of patients, and found out complication of RFA. RESULTS: Cumulative recurrence rates in 3, 6, 12 months after RFA was 8.8%, 15.8%, 25.9%. 12 cases were recurred during follow-up. Among them, intrahepatic recurrences were noted in 11 cases, local recurrences in 3 cases. Cumulative survival curves indicated that survival rate was 95% at the third month, 94% at the sixth month, 81% at the twelfth month. After RFA, the alpha fetoprotein level was decreased significantly after 1 month (p<0.05), and serum transaminase levels were transiently elevated (p<0.01) but returned to normal within one week. Complications of RFA were not serious, and resolved spontaneously. CONCLUSION: RFA can be considered a useful new treatment for HCC. Laparoscopic RFA is a useful procedure for the treatment of HCC regardless of its location.
Key words
Full text:
1
Database:
WPRIM
Main subject:
English Abstract
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Tomography, X-Ray Computed
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Catheter Ablation
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Laparoscopy
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Ultrasonography, Interventional
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Carcinoma, Hepatocellular
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Liver Neoplasms
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Neoplasm Recurrence, Local
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Ko
Journal:
The Korean Journal of Hepatology
Year:
2002
Document type:
Article