An 11-year review of dermatomyositis in Asian patients
Annals of the Academy of Medicine, Singapore
; : 843-847, 2010.
Article
in En
| WPRIM
| ID: wpr-237382
Responsible library:
WPRO
ABSTRACT
<p><b>INTRODUCTION</b>Dermatomyositis (DM) is a multisystem inflammatory disease with a strong association with malignancy. We aimed to describe a series of Asian patients with DM and identify any significant clinical factors associated with malignancy.</p><p><b>MATERIALS AND METHODS</b>This was a retrospective review of a multi-racial cohort of 69 Asian patients diagnosed with DM over an 11-year period from 1996 to 2006.</p><p><b>RESULTS</b>Malignancy was detected in 15 out of 68 patients (22%), the most common of which was nasopharyngeal carcinoma (7 cases). Compared to the non-malignancy group, the malignancy-associated group was older and had more male patients. There were no statistically significant clinical, serological or laboratory factors associated with a higher risk of malignancy.</p><p><b>CONCLUSION</b>This study highlights the importance of ongoing malignancy screening especially for nasopharyngeal carcinoma in Asian patients with DM.</p>
Full text:
1
Database:
WPRIM
Main subject:
Paraneoplastic Syndromes
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Pathology
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Singapore
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Carcinoma
/
Confidence Intervals
/
Logistic Models
/
Odds Ratio
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Nasopharyngeal Neoplasms
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Epidemiology
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Retrospective Studies
Type of study:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limits:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
Country/Region as subject:
Asia
Language:
En
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2010
Document type:
Article